lca

lca identifies the lowest common ancestor (LCA) from BLAST tabular files to support phylogenetic and evolutionary analyses of sequences produced by next-generation DNA sequencing.


Key Features:

  • Lowest Common Ancestor Identification: Determines the LCA from BLAST tabular outputs to provide insights into evolutionary relationships and lineage tracing.
  • Galaxy Project Integration: Operates within the Galaxy Project environment for execution as part of Galaxy workflows.
  • Transparency and Reproducibility: Tracks analysis details automatically to support reproducibility of results.

Scientific Applications:

  • Phylogenetic Analysis: Enables exploration of evolutionary relationships among organisms by identifying common ancestors in genomic datasets.
  • Biomedical Research: Supports large-scale analyses of sequencing data for biomedical studies and interpretation of high-throughput datasets.

Methodology:

Parses BLAST tabular files to extract relevant sequence information and applies algorithms to determine the lowest common ancestor, with implementation for execution within the Galaxy framework.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
11/25/2024

Operations

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Links