lca

lca identifies the lowest common ancestor (LCA) from BLAST tabular files to support phylogenetic and evolutionary analyses of sequences produced by next-generation DNA sequencing.


Key Features:

  • Lowest Common Ancestor Identification: Determines the LCA from BLAST tabular outputs to provide insights into evolutionary relationships and lineage tracing.
  • Galaxy Project Integration: Operates within the Galaxy Project environment for execution as part of Galaxy workflows.
  • Transparency and Reproducibility: Tracks analysis details automatically to support reproducibility of results.

Scientific Applications:

  • Phylogenetic Analysis: Enables exploration of evolutionary relationships among organisms by identifying common ancestors in genomic datasets.
  • Biomedical Research: Supports large-scale analyses of sequencing data for biomedical studies and interpretation of high-throughput datasets.

Methodology:

Parses BLAST tabular files to extract relevant sequence information and applies algorithms to determine the lowest common ancestor, with implementation for execution within the Galaxy framework.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Phylogenetic tree analysis

Inputs

Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Links