LEMMI

LEMMI performs continuous benchmarking of metagenomics classifiers to evaluate read-classification methods for metagenome composition assessment in microbiome and microbial genomics research.


Key Features:

  • Continuous Benchmarking: Performs ongoing evaluations that integrate newly published and previously assessed metagenomics classification methods for up-to-date comparative results.
  • Centralized Integration: Integrates submitted methods into an independent benchmarking framework for direct comparative evaluation across tools.
  • Community-Driven Evaluation: Accepts community submissions of novel methods to enable unbiased comparative benchmarking.
  • Software Containerization: Requires distribution of evaluated methods as software containers to ensure reproducibility and preservation of evaluation artifacts.
  • Read-Classification Focus: Targets read-classification methods specifically for metagenome composition assessments.
  • Benchmark Outcome Recording: Documents evaluation results to support comparative analysis and method selection.

Scientific Applications:

  • Benchmarking Metagenomics Classifiers: Provides comparative performance data for metagenomics classifiers used in microbiome studies.
  • Method Validation and Selection: Supports validation and selection of read-classification methods for metagenome composition analyses.
  • Microbial Genomics Research Support: Aids microbial genomics research by enabling comparison of computational methods that interpret sequencing-derived microbial genotypic data.
  • Evaluation of New Methods: Facilitates assessment of newly developed classifiers against established tools.

Methodology:

LEMMI evaluates both previously assessed and newly submitted tools, focuses on read-classification methods for metagenome composition assessment, enforces distribution of methods as software containers, and records the outcomes of these evaluations.

Topics

Details

Tool Type:
api
Added:
1/18/2021
Last Updated:
2/12/2021

Operations

Publications

Seppey M, Manni M, Zdobnov EM. LEMMI: a continuous benchmarking platform for metagenomics classifiers. Genome Research. 2020;30(8):1208-1216. doi:10.1101/gr.260398.119. PMID:32616517. PMCID:PMC7462069.

PMID: 32616517
PMCID: PMC7462069
Funding: - National Science Foundation: 310030_189062, 31003A_166483

Documentation

Links