LncTar

LncTar predicts RNA targets of long noncoding RNAs (lncRNAs) at large scale to identify lncRNA-RNA interactions relevant to gene regulation.

Key Features:

• Large-Scale Prediction: Performs large-scale prediction of RNA targets for lncRNAs across large datasets.
• Accuracy and Reliability: Was benchmarked on 10 experimentally supported lncRNA-mRNA interactions and correctly predicted 8 of 10 (80%).

Scientific Applications:

• Elucidation of lncRNA function: Supports identification of lncRNA-RNA interactions to elucidate functional roles of lncRNAs.
• Gene regulation and epigenetics studies: Enables analyses of RNA-RNA regulatory interactions relevant to gene regulation and epigenetic mechanisms.
• Disease mechanism and therapeutic target investigation: Facilitates investigation of disease mechanisms and potential therapeutic targets via predicted lncRNA-RNA interactions.

Methodology:

LncTar leverages advanced computational algorithms tailored for the prediction of lncRNA-RNA interactions.