M2OR

M2OR curates 75,050 bioassay experiments covering 51,395 olfactory receptor (OR)-molecule pairs to enable analysis of OR–ligand interactions and investigation of olfactory coding.

Key Features:

• Extensive Data Collection: Compiles 75,050 bioassay experiments covering 51,395 distinct OR-molecule pairs, including responses to individual molecules and mixtures.
• Receptor Sequences and Experimental Metadata: Includes receptor sequences and detailed experimental parameters such as species and assay systems.
• Curated Sources: Aggregates data extracted from published literature and public databases.
• Advanced Search Capabilities: Enables fine-grained queries using metadata parameters including species and experimental assay systems.
• Batch Query Functionality: Supports batch searches allowing multiple queries to be submitted simultaneously.
• Data Aggregation and Export: Provides curated aggregation of experimental results for queries and allows download as a binarized combinatorial code of olfaction.

Scientific Applications:

• Molecular recognition spectrum of ORs: Enables study of the molecular recognition spectrum and ligand specificity of olfactory receptors.
• Sensory biology research: Supports basic research into olfactory perception and sensory biology by providing experimental response data.
• Applied technologies and therapeutics: Supports applied studies aimed at developing technologies or therapeutic approaches based on olfactory mechanisms.

Methodology:

Data curation from published literature and public databases, aggregation of experimental assay results including responses to individual molecules and mixtures, and export of query results as a binarized combinatorial code of olfaction.