m6A2Target

m6A2Target catalogs target genes of N6-methyladenosine (m6A) writers, erasers, and readers (WERs) to support analysis of m6A-mediated posttranscriptional regulation in mammalian mRNA.

Key Features:

• Comprehensive catalog: Records target genes associated with m6A writers, erasers, and readers (WERs).
• Validated Targets: Contains targets identified through low-throughput studies.
• Potential Targets: Includes targets derived from high-throughput studies.

Scientific Applications:

• Elucidating Mechanisms: Enables investigation of regulatory mechanisms mediated by m6A modifications on mRNA.
• Functional Studies: Supports selection of validated versus potential targets for experimental validation of gene function.
• Comparative Analysis: Facilitates comparison of WER target profiles across conditions or datasets to identify context-specific targeting.

Methodology:

Targets are categorized into "Validated Targets" from low-throughput studies and "Potential Targets" from high-throughput studies.