M6AREG

M6AREG compiles and organizes data on N6-methyladenosine (m6A)-centered regulation to document effects on disease development and drug response.


Key Features:

  • Systematic Coverage: Compiles data on the effects of m6A-centered regulation across disease development and drug response in a centralized collection.
  • Molecular Mechanism Annotation: Describes the molecular mechanisms underlying each reported m6A-centered regulatory event.
  • Cross-referencing: Links collected entries to existing databases to enable verification and integration with other resources.

Scientific Applications:

  • Pathology and Pathophysiology: Enables exploration of how m6A modifications influence disease mechanisms and potential biomarker or target identification.
  • Clinical Laboratory Diagnostics: Provides data that can inform development of diagnostic approaches based on m6A-related changes.
  • Medicinal Biochemistry and Drug Design: Supports investigation of m6A roles in drug response to inform drug design and therapeutic strategy development.

Methodology:

M6AREG integrates diverse datasets related to m6A-centered regulation, systematically organizes the information for each entry, and cross-references collected data to existing databases.

Topics

Details

License:
Not licensed
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
11/9/2022
Last Updated:
11/24/2024

Operations

Publications

Liu S, Chen L, Zhang Y, Zhou Y, He Y, Chen Z, Qi S, Zhu J, Chen X, Zhang H, Luo Y, Qiu Y, Tao L, Zhu F. M6AREG: m6A-centered regulation of disease development and drug response. Nucleic Acids Research. 2022;51(D1):D1333-D1344. doi:10.1093/nar/gkac801. PMID:36134713. PMCID:PMC9825441.

PMID: 36134713
PMCID: PMC9825441
Funding: - Natural Science Foundation of Zhejiang Province: LQ17H160009, LR21H300001 - National Natural Science Foundation of China: 81802371, 81872798 - Fundamental Research Fund of Central University: 2018QNA7023 - Key R&D Program of Zhejiang Province: 2020C03010 - Chinese ‘Double Top-Class’ Universities: 181201*194232101 - Start-up Grant of HZNU: 4125C5021720421 - China Scholarship Council: 201908330151