maCorrPlot

maCorrPlot visualizes correlations in microarray data to identify spurious associations resulting from insufficient normalization.


Key Features:

  • Graphical visualization: Creates plots that reveal correlations in microarray datasets that may be artifacts of inadequate normalization.
  • R implementation: Implemented in the R statistical programming language.
  • Bioconductor integration: Operates within the Bioconductor ecosystem for interoperability with other Bioconductor packages and genomic datasets.
  • Community-driven development: Contributed and maintained by the Bioconductor community with initial review and automated testing to ensure reliability and accuracy.

Scientific Applications:

  • Normalization assessment: Detects and visualizes correlations arising from insufficient normalization in microarray experiments to guide normalization improvements.
  • Genomics and gene expression quality control: Supports quality assessment of high-throughput gene expression analyses in genomics and molecular biology.

Methodology:

Uses statistical methods implemented in R to detect and visualize spurious correlations in microarray datasets resulting from inadequate normalization.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

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