maCorrPlot
maCorrPlot visualizes correlations in microarray data to identify spurious associations resulting from insufficient normalization.
Key Features:
- Graphical visualization: Creates plots that reveal correlations in microarray datasets that may be artifacts of inadequate normalization.
- R implementation: Implemented in the R statistical programming language.
- Bioconductor integration: Operates within the Bioconductor ecosystem for interoperability with other Bioconductor packages and genomic datasets.
- Community-driven development: Contributed and maintained by the Bioconductor community with initial review and automated testing to ensure reliability and accuracy.
Scientific Applications:
- Normalization assessment: Detects and visualizes correlations arising from insufficient normalization in microarray experiments to guide normalization improvements.
- Genomics and gene expression quality control: Supports quality assessment of high-throughput gene expression analyses in genomics and molecular biology.
Methodology:
Uses statistical methods implemented in R to detect and visualize spurious correlations in microarray datasets resulting from inadequate normalization.
Topics
Collections
Details
- License:
- GPL-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.