MakeHub

MakeHub generates UCSC Genome Browser Assembly Hubs to visualize annotated genomes and associated genomic tracks.

Key Features:

• Automation: Automates the generation of the components required for an Assembly Hub.
• Extensibility: Supports addition of new tracks to existing Assembly Hubs.
• File format handling: Processes and adapts input file formats to ensure compatibility with UCSC Genome Browser requirements.
• Automated pipeline: Executes a reproducible pipeline that assembles necessary hub files from provided inputs.

Scientific Applications:

• Genome visualization: Enables visualization of annotated genomes and associated data tracks in the UCSC Genome Browser.
• Quality control: Facilitates quality control of genome annotations and derived genomic data.
• Annotation dissemination: Supports sharing and updating genome annotations via Assembly Hubs.

Methodology:

MakeHub runs a fully automated pipeline that processes input files and generates the necessary components for an Assembly Hub, including handling file formats and ensuring compatibility with UCSC Genome Browser requirements.