MALPACA
MALPACA automates multi-template landmark placement to generate reproducible landmark datasets for quantitative morphological and evolutionary analyses.
Key Features:
- Multiple Template Utilization: Employs multiple templates to accommodate large-scale morphological variation and reduce bias associated with single-template approaches.
- K-means Template Selection: Uses K-means clustering to select representative templates when no prior template information is available.
- Point Cloud Alignment and Correspondence Analysis: Aligns point clouds and performs correspondence analysis across multiple templates to identify landmark positions.
- Improved Accuracy and Consistency: Demonstrates superior accuracy and consistency relative to single-template methods across diverse samples.
- Post-hoc Quality Assessment: Provides per-template post-hoc quality checks to evaluate and refine landmarking results.
Scientific Applications:
- Evolutionary Biology: Facilitates quantitative analyses of morphological phenotypes for evolutionary inference.
- Comparative Morphometrics: Supports landmarking in single- and multi-species studies with significant morphological variability.
- Population and Phenotypic Variation Studies: Enables reproducible landmark datasets for studies of morphological variation among populations or taxa.
Methodology:
Aligns point clouds, performs correspondence analysis using multiple templates, and integrates K-means clustering for template selection.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- desktop application
- Operating Systems:
- Windows, Linux
- Added:
- 2/23/2023
- Last Updated:
- 11/24/2024
Operations
Publications
Zhang C, Porto A, Rolfe S, Kocatulum A, Maga AM. Automated landmarking via multiple templates. PLOS ONE. 2022;17(12):e0278035. doi:10.1371/journal.pone.0278035. PMID:36454982. PMCID:PMC9714854.
PMID: 36454982
PMCID: PMC9714854
Funding: - Division of Biological Infrastructure: ABI1759883
- National Institute of Dental and Craniofacial Research: R03DE027110