MANTA_DB
MANTA_DB correlates microbiota composition with host phenotypic traits to enable integrative analysis of microbial community–phenotype relationships.
Key Features:
- Integrative Database: Centralized storage and management of microbiota and phenotypic datasets to enable joint analyses of microbial abundances and host traits.
- Correlation Analysis: Statistical identification of significant associations between microbial abundances and host phenotypic variables.
- Computational Mapping and Interpretation: Analytical procedures to map, analyze, and interpret relationships between microbiota composition and host phenotypes rather than focusing solely on taxonomic profiling or group comparisons.
Scientific Applications:
- Correlation discovery: Identification of significant correlations between microbial abundances and phenotypic traits.
- Research domains: Application to studies in personalized medicine, nutrition, and disease pathogenesis involving microbiome–host trait associations.
Methodology:
Computational methods map, analyze, and interpret relationships between microbiota composition and host phenotypes and perform direct correlation analysis instead of primarily conducting taxonomic profiling or comparative group analysis.
Topics
Details
- License:
- MIT
- Tool Type:
- command-line tool, web application
- Programming Languages:
- Java
- Added:
- 1/18/2021
- Last Updated:
- 2/19/2021
Operations
Publications
Chen Y, Park J, Natsume-Kitatani Y, Kawashima H, Mohsen A, Hosomi K, Tanisawa K, Ohno H, Konishi K, Murakami H, Miyachi M, Kunisawa J, Mizuguchi K. MANTA, an integrative database and analysis platform that relates microbiome and phenotypic data. PLOS ONE. 2020;15(12):e0243609. doi:10.1371/journal.pone.0243609. PMID:33275647. PMCID:PMC7717536.