maskambigprot

maskambigprot masks the ambiguity character 'X' in protein sequences to remove unknown or unspecified amino-acid residues that can compromise downstream computational analyses.


Key Features:

  • Ambiguity Masking: Systematically identifies and masks all instances of the ambiguity character 'X' in protein sequences, where 'X' represents unknown or unspecified amino acids.
  • Integration with EMBOSS: Operates as part of the EMBOSS suite and interoperates with over 200 other molecular biology applications for downstream processing.
  • Extensible Libraries: Implemented using EMBOSS's C programming libraries to provide robustness and extensibility.

Scientific Applications:

  • Data Cleaning: Masks ambiguous residues to improve the quality of protein sequence data for analyses such as homology modeling, phylogenetic studies, and functional annotation.
  • Sequence Analysis: Provides higher-quality input for downstream bioinformatics tools, improving the reliability of computational results in molecular biology workflows.

Methodology:

The program systematically identifies and masks all 'X' characters in protein sequences and is implemented using EMBOSS's C programming libraries.

Topics

Collections

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
C
Added:
11/8/2015
Last Updated:
12/10/2018

Operations

Publications

Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.

Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.

Documentation

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