maskfeat
maskfeat masks specified sequence features to generate sequences with masked regions for targeted analyses in genomics and proteomics.
Key Features:
- Feature masking: Generates sequences with specified features masked, allowing selective obscuring of sequence regions and motifs.
- EMBOSS integration: Operates as part of the EMBOSS suite, enabling reuse of EMBOSS components and compatibility with other EMBOSS applications.
- EMBOSS C libraries: Built on the EMBOSS C programming libraries for core implementation.
- ACD file support: Uses ACD file development to describe and customize application parameters and interfaces.
- API compliance: Implements EMBOSS API programming guidelines for application structure and behavior.
- Wrapping and porting: Supports wrapping and porting to incorporate third-party tools.
Scientific Applications:
- Sequence Analysis: Masks selected features to focus analyses on regions of interest in comparative genomics and evolutionary studies.
- Data Privacy: Masks sensitive sequence information to facilitate sharing while protecting confidential elements of sequence data.
- Functional Genomics: Masks non-coding regions or repetitive elements to concentrate analysis on coding sequences for gene function and regulation studies.
- Proteomics: Masks specific amino acid motifs to aid analysis of protein structure and function.
Methodology:
Implemented using EMBOSS C libraries, with ACD file development for application descriptions, adherence to EMBOSS API programming guidelines, and support for wrapping/porting third-party tools.
Topics
Collections
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- C
- Added:
- 11/8/2015
- Last Updated:
- 12/10/2018
Operations
Data Inputs & Outputs
Sequence masking
Inputs
Outputs
Publications
Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.
Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.
Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.