matFR

matFR implements 42 feature-ranking methods in MATLAB to identify informative and discriminative features from large biological and clinical datasets for applications such as precision medicine.


Key Features:

  • Integration of Methods: Incorporates 42 diverse feature ranking methods, including 12 from FSLib, 9 mutual information-based methods, and 7 native MATLAB functions such as "rankfeatures", "relieff", and "lasso".
  • Supervised vs. Unsupervised Methods: Provides 29 supervised and 13 unsupervised feature ranking methods.
  • Theoretical Categorization: Implements method categories including 12 mutual information-based methods, 8 statistical analysis-based methods, and 8 structure learning-based methods.

Scientific Applications:

  • Precision Medicine: Enables ranking of features to identify candidate biomarkers and characteristics relevant to diagnosis, prognosis, and treatment strategies.
  • Data Interpretation: Facilitates comparison, investigation, and interpretation of selected features across datasets to aid understanding of complex biological and clinical data.
  • Medical Imaging: Has been applied to sorting mammographic breast lesion features, demonstrating utility in medical imaging and diagnostics.

Methodology:

The integrated methods apply principles such as mutual information, statistical analysis, and structure clustering to estimate feature importance within specific measure spaces.

Topics

Details

Tool Type:
library
Programming Languages:
MATLAB
Added:
1/18/2021
Last Updated:
2/20/2021

Operations

Publications

Zhang Z, Liang X, Qin W, Yu S, Xie Y. matFR: a MATLAB toolbox for feature ranking. Bioinformatics. 2020;36(19):4968-4969. doi:10.1093/bioinformatics/btaa621. PMID:32637981.

PMID: 32637981
Funding: - Shenzhen Matching Project: GJHS20170314155751703 - National Key Research and Develop Program of China: 2016YFC0105102 - National Natural Science Foundation of China: 61871374 - Leading Talent of Special Support Project in Guangdong: 2016TX03R139 - Science Foundation of Guangdong: 2015B02023301, 2017B020229002