Maxillary-Sinus-Quantification

Maxillary-Sinus-Quantification quantifies total and air-free volumes of the maxillary sinus from computed tomography (CT) images to provide standardized, reproducible measurements for research and clinical comparisons.

Key Features:

• Automation: Automates segmentation and volume measurement to eliminate manual or semi-automated segmentation steps.
• Volume types: Reports both total volume and air-free volume of the maxillary sinus from CT images.
• Standardization: Applies consistent image processing techniques including watershed algorithms, thresholding, and morphological operations to ensure uniform measurements across datasets.
• Accuracy and Reliability: Validated on 30 patients with mean percent differences of 7.19% ± 5.83% for total volume and 6.93% ± 4.29% for air-free volume versus manual segmentation by an experienced radiologist.
• Statistical Validation: Uses linear regression analysis and Bland–Altman statistics to assess agreement and dispersion between automated and manual measurements.

Scientific Applications:

• Disease Identification: Enables detection and quantification of paranasal sinus pathology through volumetric assessment of the maxillary sinus.
• Comparative Studies: Provides standardized volume measurements to improve accuracy and comparability across clinical and research studies.
• Research on Maxillary Sinus Factors: Supports investigations of factors influencing maxillary sinus size under normal and pathological conditions.

Methodology:

Processes CT images using watershed algorithm, thresholding, and morphological operators to delineate boundaries and separate air-filled from tissue regions, with validation by comparison to manual segmentation using linear regression and Bland–Altman statistics.