mBrainAligner-Web

mBrainAligner-Web performs cross-modal coherent registration of whole mouse brains to align images from multiple imaging modalities for integrative analysis of brain structure.

Key Features:

• Cross-modal coherent registration: Aligns brain images obtained through different imaging modalities to enable integration across modalities.
• mBrainAligner pipeline: Implements the mBrainAligner whole-brain registration framework to provide robust, coherent alignment of whole mouse brains.
• Support for diverse experimental data: Handles datasets produced by whole-brain mapping projects that use diverse imaging, labeling, and sample preparation techniques.

Scientific Applications:

• Neuroanatomical integration: Integrates high-resolution brain imaging data across modalities to compare anatomical and molecular patterns in mouse brains.
• Whole-brain mapping analysis: Supports analysis and consolidation of datasets from whole-brain mapping projects that employ varied imaging, labeling, and sample preparation methods.

Methodology:

Configuration of the mBrainAligner pipeline, selection of registration parameters, and execution of cross-modal coherent alignment of whole mouse brain images.