MCRestimate

MCRestimate estimates misclassification error rates for genomic classification by integrating preprocessing and classification methods within the Bioconductor/R ecosystem.


Key Features:

  • Integration of Preprocessing and Classification: Integrates preprocessing techniques with classification algorithms to enable estimation of misclassification errors.
  • Misclassification Error Calculation: Computes misclassification error estimates to quantify predictive model performance in genomic analyses.
  • Bioconductor Platform: Implements functionality within the Bioconductor project using the R programming language.
  • Interoperability: Interoperates with 934 Bioconductor packages to integrate into existing genomic analysis workflows.
  • Formal Review and Testing: Is subject to Bioconductor's formal initial review and continuous automated testing for quality assurance.

Scientific Applications:

  • Genomic Data Analysis: Provides misclassification error estimates for analyses of high-throughput genomic data.
  • Model Performance Evaluation: Enables evaluation and comparison of predictive models via quantified misclassification rates.
  • Interdisciplinary Research: Supports integration of genomic classification methods across interdisciplinary projects through Bioconductor package interoperability.

Methodology:

Integrates preprocessing steps with classification algorithms to compute misclassification error estimates.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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