merger

merger merges overlapping sequences to identify and integrate overlapping regions for sequence assembly and downstream genomic analyses within EMBOSS.


Key Features:

  • Core merging algorithm: Implements algorithms to detect and integrate overlaps between sequences to produce merged sequences.
  • EMBOSS integration: Part of the EMBOSS suite of over 200 applications, enabling interoperability with other EMBOSS programs and third-party bioinformatics software.
  • Extensibility and customization: Built on EMBOSS C libraries and supports ACD file development to extend or customize functionality.
  • API and portability: Exposes EMBOSS C libraries and APIs and supports wrapping and porting third-party applications within EMBOSS.

Scientific Applications:

  • Genomic studies: Supports combining overlapping sequences for genomic analyses.
  • Genome assembly: Merges overlapping sequence fragments to support genome assembly workflows.
  • Sequence alignment: Produces continuous merged sequences for sequence alignment analyses.
  • Comparative genomics: Generates merged sequences for comparative genomics analyses.

Methodology:

The methodology involves sophisticated algorithms that identify and integrate overlapping regions within sequences and leverages the EMBOSS toolkit to process large datasets for sequence assembly and analysis.

Topics

Collections

Details

License:
GPL-3.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Windows, Mac
Programming Languages:
C
Added:
11/8/2015
Last Updated:
12/10/2018

Operations

Publications

Rice P, Longden I, Bleasby A. EMBOSS: The European Molecular Biology Open Software Suite. Trends in Genetics. 2000;16(6):276-277. doi:10.1016/s0168-9525(00)02024-2.

Bleasby AJ, Ison JC, Rice PM. EMBOSS Administrator's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151399.

Ison JC, Rice PM, Bleasby AJ. EMBOSS Developer's Guide. Unknown Journal. 2011. doi:10.1017/cbo9781139151405.

Documentation

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