Metabolite_AutoPlotter

Metabolite_AutoPlotter generates individual plots and processed outputs from quantified metabolite-intensity tables to visualize metabolite-level changes and support analysis of metabolomics and stable isotope tracing experiments.

Key Features:

• Automated Plot Generation: Generates individual plots for each metabolite rather than bulk heat maps to enable per-metabolite inspection.
• Flexible Input Handling: Accepts pre-processed metabolite-intensity tables and accommodates varying numbers of metabolites, conditions, and replicates.
• Natural Abundance Correction: Performs natural abundance correction for stable isotope tracing data, including ^13C-labeled compounds.
• Implementation: Implemented in R.
• Efficient Output Management: Produces a zip file containing individual metabolite plots and restructured tables for downstream analysis.

Scientific Applications:

• Stable Isotope Tracing: Supports analysis and interpretation of ^13C-labeling experiments through natural abundance correction and per-metabolite visualization.
• Metabolomics Data Visualization: Provides per-metabolite plots to aid visualization and comparison of quantified metabolite intensities.
• Systems Biology: Enables examination of metabolite-level changes relevant to systems biology studies.
• Pharmacology and Clinical Research: Facilitates analysis and reporting of metabolite-level responses in pharmacology and clinical metabolomics studies.

Methodology:

Accepts pre-processed metabolite-intensity tables, generates individual metabolite plots, applies natural abundance correction for ^13C-labeled data, is implemented in R, and outputs a zip file containing plots and restructured tables.