MetaboMAPS

MetaboMAPS visualizes numerical experimental data on metabolic pathway maps to contextualize metabolites, enzymes, and regulators within metabolic networks.

Key Features:

• SVG format support: Stores, distributes, and allows downloading of metabolic maps in SVG format for scalable, high-fidelity pathway representations.
• Customizable visualization: Plots user-provided numerical datasets directly onto pathway maps to map experimental results to pathway components.
• Plot box editor: Defines and modifies plot boxes on pathway maps and assigns identifiers to link data regions to specific metabolites or reactions.
• Flexible pathway sharing: Supports sharing of pathway maps without enforcing strict conventions, accommodating individualized or noncanonical pathway representations.
• Support for custom pathways: Accepts and visualizes user-defined pathways beyond established pathway databases or standard annotations.

Scientific Applications:

• Systems biology: Contextualizes experimental measurements within metabolic networks to aid analysis of metabolic interactions and regulation.
• Multi-omics integration: Maps quantitative data from diverse omics layers onto pathways to facilitate combined interpretation of metabolomics, proteomics, or transcriptomics data.
• Novel pathway analysis and dissemination: Enables visualization and sharing of individualized or less-characterized pathways for dissemination of new metabolic findings.

Methodology:

Uses SVG-format pathway maps for storage and download, plots numerical datasets onto maps, and employs a plot box editor to add or modify visualization regions and assign identifiers.