metagenomeFeatures

metagenomeFeatures provides tools to process and analyze taxonomic annotations of marker-gene metagenomic sequence datasets for taxonomic profiling of microbial communities.


Key Features:

  • Taxonomic Exploration: Enables inspection of the taxonomic composition of marker-gene databases and annotated sequences derived from metagenomic experiments.
  • Interoperability with Bioconductor: Integrates with Bioconductor to interoperate with other Bioconductor packages and exchange data structures.
  • R-Based Framework: Implements functionality within the R statistical programming environment for statistical analysis of sequence-derived taxonomic data.
  • Community-Driven Development: Distributed via Bioconductor with formal initial review and continuous automated testing to ensure code quality.

Scientific Applications:

  • Microbial ecology: Enables taxonomic profiling and diversity analysis to investigate microbial community structure.
  • Environmental microbiology: Supports analysis of marker-gene datasets from environmental samples to characterize taxa across ecosystems.
  • Human-associated microbiomes: Facilitates taxonomic investigations of human-associated microbiomes to assess microbial diversity and potential functional composition.

Methodology:

Processing and annotation of marker-gene sequences using sequence alignment, database comparison, and statistical analysis, with integration into Bioconductor packages.

Topics

Collections

Details

License:
Artistic-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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