MetAMDB

MetAMDB provides comprehensive atom mappings for approximately 43,000 metabolic reactions to support 13C metabolic flux analysis (MFA) and enable tracking of individual atoms through metabolic models.

Key Features:

• Comprehensive atom mappings: Includes atom mappings for approximately 43,000 metabolic reactions.
• File formats: Atom mappings are available as RXN files and as SVG graphics.
• Custom model generation: Supports generation of user-defined atom mapping models for networks ranging from small reaction sets to genome-scale networks.
• Compatibility with MFA software: Generated models are compatible with standard 13C metabolic flux analysis (MFA) software.
• Atom-level tracking: Enables precise tracking of individual atoms through complex biochemical pathways.

Scientific Applications:

• 13C metabolic flux analysis (MFA): Provides atom mappings and models to support interpretation and analysis in 13C MFA studies.
• Metabolic modeling: Facilitates construction and analysis of metabolic models from small-scale to genome-scale networks.
• Atom tracing in pathways: Enables studies that require tracking of atom transitions across biochemical reactions.

Methodology:

Atom mappings are provided as RXN files and SVG graphics, and custom atom mapping models can be generated for networks ranging from small reaction sets to genome-scale networks for integration with standard 13C MFA software.