Metavisitor
Metavisitor assembles and detects viral genomes from deep sequencing datasets to identify and reconstruct viruses from DNA, RNA, and small RNA sequencing across a range of read lengths.
Key Features:
- Modular workflows and Galaxy integration: A suite of modular bioinformatic tools and workflows integrated within the Galaxy framework for configurable computational analyses.
- Versatile data compatibility: Supports DNA, RNA, and small RNA sequencing data across a range of read lengths.
- De novo and guided assembly: Employs both de novo and guided assembly strategies to reconstruct viral genomes from sequencing reads.
- Rapid diagnostic and discovery capability: Enables rapid identification of known viruses and the discovery of novel viral entities across diverse organisms.
Scientific Applications:
- Virology: Reconstruction of viral genomes for characterization and comparative analyses.
- Epidemiology: Identification of viral agents from outbreak-associated sequencing datasets.
- Clinical diagnostics: Detection and assembly of viral genomes for diagnostic investigation of patient samples.
- Viral discovery and evolution: Discovery of novel viruses and study of viral evolution from deep sequencing data.
Methodology:
Detection and assembly of viral genomes from deep sequencing datasets using modular workflows within the Galaxy framework, employing de novo and guided assembly approaches.
Topics
Collections
Details
- Tool Type:
- command-line tool, web application
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- Shell
- Added:
- 6/2/2018
- Last Updated:
- 11/25/2024
Operations
Data Inputs & Outputs
Sequence alignment
Publications
Carissimo G, van den Beek M, Vernick KD, Antoniewski C. Metavisitor, a Suite of Galaxy Tools for Simple and Rapid Detection and Discovery of Viruses in Deep Sequence Data. PLOS ONE. 2017;12(1):e0168397. doi:10.1371/journal.pone.0168397. PMID:28045932. PMCID:PMC5207757.
PMID: 28045932
PMCID: PMC5207757
Funding: - Agence Nationale de la Recherche: ANR-10-LABX-62-IBEID, ANR-13-BSV2-0007 « Plastisipi »
- Institut Universitaire d’Ingéniérie en Santé IUIS: ARTiMED
- European Research Council: Advanced Grant #323173 AnoPath
- European Commission: FP7 Infrastructures #228421 Infravec
Documentation
User manual
https://artbio.github.io/Metavisitor-manual/