metavizr

metavizr provides interactive exploratory analysis of annotated microbiome taxonomic community profiles derived from marker gene sequencing or whole metagenome shotgun sequencing.


Key Features:

  • Interactive visualization: Dynamic visualizations for exploring hierarchical taxonomic feature structures in metagenomic profiles.
  • Bioconductor integration: Supports Bioconductor data structures to integrate with Bioconductor analysis workflows.
  • Input data types: Operates on annotated taxonomic community profiles derived from marker gene sequencing and whole metagenome shotgun sequencing.
  • Public data access: Accesses the UMD Metagenome Browser web service providing data from over 7,000 microbiomes from published studies.

Scientific Applications:

  • Microbial community profiling: Exploration and organization of taxonomic community profiles to study microbial community structure and dynamics.
  • Phenotype association studies: Analysis of associations between microbial community profiles and health or disease phenotypes.
  • Integrative analysis of public datasets: Comparative or integrative analyses using publicly available metagenomes from the UMD Metagenome Browser.

Methodology:

Implements dynamic visualization of hierarchical taxonomic features, integrates Bioconductor data structures, and accesses the UMD Metagenome Browser for public metagenomic datasets.

Topics

Collections

Details

License:
MIT
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
7/21/2018
Last Updated:
12/10/2018

Operations

Data Inputs & Outputs

Publications

Wagner J, Chelaru F, Kancherla J, Paulson JN, Zhang A, Felix V, Mahurkar A, Elmqvist N, Corrada Bravo H. Metaviz: interactive statistical and visual analysis of metagenomic data. Nucleic Acids Research. 2018;46(6):2777-2787. doi:10.1093/nar/gky136. PMID:29529268. PMCID:PMC5887897.

PMID: 29529268
PMCID: PMC5887897
Funding: - National Institutes of Health: RO1GM114267, U54DK102556

Documentation

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