MetazExp

MetazExp aggregates and enables comparative analysis of gene expression and alternative splicing from 53,615 uniformly processed public RNA-seq samples across 72 metazoan species.

Key Features:

• Extensive Data Repository: Contains gene expression and alternative splicing profiles derived from 53,615 public RNA-seq samples covering 72 metazoan species.
• Query Capability: Supports queries by gene IDs, gene symbols, functional terms, and sequence similarity.
• Customizable Analysis Options: Supports defining experimental groups for differential expression and species-specific expression and alternative splicing analyses.
• Data Visualization Tools: Includes integrated data visualization functions for exploring expression and splicing results.
• Integration with External Databases: Provides links for cross-referencing with external bioinformatics databases.

Scientific Applications:

• Gene Expression Studies: Comparative analysis of gene expression patterns across species or experimental conditions.
• Alternative Splicing Analysis: Characterization and comparison of alternative splicing events across conditions and species.
• Retrospective Data Analysis: Reanalysis of published RNA-seq datasets to generate new biological insights without new experiments.

Methodology:

Uniform processing of 53,615 public RNA-seq samples across 72 metazoan species to produce comparable gene expression and alternative splicing profiles.