MetDraw

MetDraw generates metabolic reaction maps to visualize genome-scale metabolic models for systems biology analyses.

Key Features:

• Automated map generation: Fully automates the drawing of metabolic reaction maps from genome-scale metabolic models to produce detailed network visualizations.
• Omics data overlay: Integrates high-throughput transcriptomics, proteomics, and metabolomics data directly onto reaction maps.
• Scalability: Produces maps that encompass hundreds to thousands of reactions for genome-scale models.
• Consistent representation: Ensures consistent and accurate graphical representation of reactions and network structure.

Scientific Applications:

• Metabolic pathway analysis: Visualizes pathways and interactions within an organism to support pathway-level interpretation.
• Functional genomics: Supports analysis of gene function and metabolic roles by mapping omics data onto models.
• Synthetic biology: Assists design and analysis of engineered metabolic pathways using genome-scale maps.
• Metabolic engineering: Facilitates identification of metabolic interventions and engineering targets.
• Model-data integration: Enables direct comparison between model predictions and empirical omics data to identify regulatory nodes and potential therapeutic targets.

Methodology:

Automatically generates reaction maps from genome-scale metabolic models and overlays transcriptomics, proteomics, and metabolomics data onto these maps.