MI-Sim

MI-Sim analyzes ecological network motifs and microbial interactions by implementing mechanistic ordinary differential equation models as an extension for MATLAB.


Key Features:

  • MATLAB extension: Implemented as an extension for MATLAB to run analyses and simulations within the MATLAB environment.
  • Ecological motif library: Includes seven ecological interaction motifs, including cooperation, competition, and predation, representing feeding relationships between consumers and producers across scales.
  • Growth function models: Incorporates seven growth function models to simulate a range of dynamic behaviors in ecological systems.
  • Numerical analysis tools: Supports model simulation, steady-state existence and stability analysis, and basin of attraction analysis for dynamical systems.
  • Mechanistic ODE modeling: Uses mechanistic mathematical modeling with ordinary differential equations to describe dynamic interactions among species or components.
  • Microbial interaction focus: Targets analysis of microbial interactions and ecological network motifs relevant to microbial ecology and biological mathematics.

Scientific Applications:

  • Microbial ecology: Simulates and analyzes microbial interaction motifs to predict dynamic behavior and assess system stability.
  • Food-web and trophic interactions: Studies feeding relationships between consumers and producers to evaluate interaction outcomes across scales.
  • Conservation biology and ecosystem management: Explores potential outcomes and stability under varied conditions to inform ecosystem-level assessments.
  • Theoretical ecology and mathematical biology: Investigates steady states, stability properties, and basins of attraction in ecological dynamical systems.

Methodology:

Mechanistic mathematical modeling using ordinary differential equations, with computational methods including model simulation, steady-state existence and stability analysis, and basin of attraction analysis.

Topics

Details

Tool Type:
plugin
Operating Systems:
Linux, Windows, Mac
Programming Languages:
MATLAB
Added:
6/4/2018
Last Updated:
11/25/2024

Operations

Publications

Wade MJ, Oakley J, Harbisher S, Parker NG, Dolfing J. MI-Sim: A MATLAB package for the numerical analysis of microbial ecological interactions. PLOS ONE. 2017;12(3):e0173249. doi:10.1371/journal.pone.0173249. PMID:28273164. PMCID:PMC5342223.

PMID: 28273164
PMCID: PMC5342223
Funding: - Biotechnology and Biological Sciences Research Council: BB/K003240/2 - Newcastle University: Institute of Sustainability - Responsive Mode

Documentation