microstate

microstate performs brain functional microstate analysis across EEG and MEG (sensor-space and source-space) and related neuroimaging modalities to characterize transient topographies and their temporal dynamics.

Key Features:

• Versatile analysis capabilities: Supports individual- and group-level analyses on resting-state and task-evoked datasets, including event-related potentials/fields (ERPs/ERFs).
• Microstate sequence visualization: Provides functions for visualizing microstate sequences and their temporal properties.
• Microstate-segmented functional connectivity: Performs functional connectivity analysis segmented by microstate labels.
• Cluster-permutation topographic ANOVAs: Implements cluster-permutation statistics for topographic ANOVAs.
• χ² analysis of microstate probabilities: Enables χ² analysis of microstate probabilities in response to stimuli.
• Simulation capabilities: Simulates microstate sequences and associated M/EEG data to generate datasets with known ground-truth microstates.
• Integration and method wrappers: Interfaces with FieldTrip, SPM, LORETA/sLORETA, EEGLAB, and Brainstorm and includes wrappers for Hidden Markov modelling (HMM-MAR) and independent component analysis (FastICA).

Scientific Applications:

• Cognitive neuroscience: Enables detailed analysis of brain microstates to study neural dynamics underlying cognition.
• Functional connectivity studies: Supports investigation of connectivity patterns within microstate-defined epochs.
• Temporal dynamics and state comparison: Facilitates analysis of the temporal structure of brain activity across different states and tasks.
• Method validation and benchmarking: Uses simulated microstate sequences and M/EEG data to validate analysis methods and test hypotheses.

Methodology:

Supports individual- and group-level analyses of resting-state and task-evoked (ERPs/ERFs) data; visualization of microstate sequences; microstate-segmented functional connectivity; cluster-permutation topographic ANOVAs; χ² analysis of microstate probabilities; simulation of microstate sequences and associated M/EEG data; and interfaces/wrappers for FieldTrip, SPM, LORETA/sLORETA, EEGLAB, Brainstorm, HMM-MAR, and FastICA.