miRNAmeConverter

miRNAmeConverter translates species-independent mature miRNA names across miRBase versions to enable name validation and consistency for cross-version and cross-species miRNA analyses.

Key Features:

• High-Throughput Translation: Automatically translates species-independent mature miRNA names across different miRBase versions.
• Validation and Version Detection: Checks the validity of miRNA names and detects the miRBase version associated with input names.
• Dependence on miRBaseVersions.db: Leverages the miRBaseVersions.db annotation package for name mapping and annotation data.

Scientific Applications:

• Genomics and Bioinformatics: Facilitates consistent miRNA naming for genomics and bioinformatics studies using multiple miRBase versions.
• Comparative and Cross-Species Studies: Enables comparison of mature miRNA datasets across species through species-independent name translation.
• Gene Regulation and Disease Research: Supports analyses of gene regulation, disease mechanisms, and therapeutic target identification by ensuring consistent miRNA annotations.

Methodology:

Uses a high-throughput algorithm to map species-independent mature miRNA names across miRBase versions by leveraging annotations from the miRBaseVersions.db package.