MitopatHs
MitopatHs provides curated logical and graphical representations of biochemical pathways within human mitochondria to support research on energy metabolism, ion homeostasis, and cell death.
Key Features:
- Comprehensive Pathway Visualization: Presents biochemical pathways as sequences of reactions in a logical view that represents stepwise biochemical deductions.
- Graphical Visualization: Provides a graphical view that displays and allows analysis of each step within mitochondrial pathways.
- Manually Curated Content: Contains manually curated pathway entries assembled by experts to ensure accurate and up-to-date information.
Scientific Applications:
- Energy metabolism: Enables analysis of mitochondrial energy production processes.
- Ion homeostasis: Supports study of mitochondrial ion regulation mechanisms.
- Apoptosis and cell death: Facilitates investigation of apoptosis and programmed cell death pathways involving mitochondria.
Methodology:
Integration of various mitochondrial databases to create a unified platform presenting pathway information in both logical and graphical formats.
Topics
Details
- License:
- GPL-3.0
- Tool Type:
- web application
- Programming Languages:
- PHP
- Added:
- 10/10/2021
- Last Updated:
- 10/10/2021
Operations
Publications
Marchi S, Zanella M, Pinton P, Crafa S, Boniolo G. MitopatHs: A new logically-framed tool for visualizing multiple mitochondrial pathways. iScience. 2021;24(4):102324. doi:10.1016/j.isci.2021.102324. PMID:33889820. PMCID:PMC8050385.
PMID: 33889820
PMCID: PMC8050385
Funding: - Fondazione Telethon: 2017 E5L5P3, GGP11139B
- Associazione Italiana per la Ricerca sul Cancro: IG-23670
- Ministero della Salute: GR-2016-02364602
Documentation
API documentation
https://web.math.unipd.it/mitopaths/documentation/apiLinks
Repository
https://github.com/mitopaths/websiteIssue tracker
https://github.com/mitopaths/website/issues