MMDB_Mouse

MMDB_Mouse provides taxonomic profiling of the healthy mouse gastrointestinal microbiome using 16S rRNA gene-based sequencing data.


Key Features:

  • Comprehensive Taxonomic Profiles: Compiles taxonomic profiles from 554 healthy mouse samples aggregated from 14 distinct projects.
  • Curated Metadata: Includes manually curated metadata linked to taxonomic profiles.
  • Strain-Specific Insights: Reports variation in microbial composition across mouse strains, gastrointestinal locations, genotypes, and vendors.

Scientific Applications:

  • Metabolic and Immune System Research: Supports studies on how microbiota influence host metabolism and immune responses.
  • Neurodevelopmental Studies: Enables investigation of gut microbiota-brain interactions in murine models.
  • Pre-Clinical Experimentation: Provides baseline microbiome data for experiments involving gastrointestinal health and disease models.

Methodology:

Construction involved compiling 16S rRNA gene-based taxonomic profiles from 554 healthy mouse gastrointestinal samples across 14 distinct projects.

Topics

Details

Tool Type:
web application
Added:
1/9/2020
Last Updated:
12/29/2020

Operations

Publications

Yang J, Park J, Park S, Baek I, Chun J. Introducing Murine Microbiome Database (MMDB): A Curated Database with Taxonomic Profiling of the Healthy Mouse Gastrointestinal Microbiome. Microorganisms. 2019;7(11):480. doi:10.3390/microorganisms7110480. PMID:31652812. PMCID:PMC6920994.

PMID: 31652812
PMCID: PMC6920994
Funding: - Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET): 918013-04-2-SB010

Links