modifygenomiccoordinates

modifygenomiccoordinates adjusts genomic coordinates by extending or shrinking genomic intervals to prepare regions for analysis of next-generation sequencing (NGS) and other high-throughput genomic datasets.


Key Features:

  • Coordinate Manipulation: Adjusts genomic coordinates by extending or shrinking intervals to modify region boundaries.
  • Galaxy Integration: Executes within the Galaxy project computational infrastructure for workflow integration.
  • Provenance Tracking: Automatically logs actions and analysis steps to enable reproducibility and inspection.
  • Support for Large-Scale Analyses: Handles coordinate adjustments suitable for processing large NGS and biomedical datasets.

Scientific Applications:

  • Data Preparation: Prepares genomic region sets by resizing intervals for downstream analyses and pipelines.
  • Reproducibility: Provides automatically logged provenance to support reproducible computational analyses.
  • Large-Scale NGS Processing: Facilitates management of interval definitions in large-scale next-generation sequencing workflows.

Methodology:

Performs coordinate extension and shrinking and utilizes the Galaxy project computational infrastructure with automated provenance logging.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links