MODOMICS

MODOMICS curates a comprehensive database of RNA modifications, documenting chemical structures of modified ribonucleosides, their biosynthetic pathways, precise locations within RNA sequences, and the enzymes that catalyze these modifications.

Key Features:

• Chemical Structures: Catalogs the chemical structures of modified ribonucleosides.
• Biosynthetic Pathways: Documents biosynthetic pathways involved in the formation of RNA modifications.
• Location Data: Provides precise locations of modified residues within RNA sequences.
• RNA-Modifying Enzymes: Lists enzymes that catalyze RNA modifications.

Scientific Applications:

• Functional Genomics: Elucidating how RNA modifications influence post-transcriptional regulation and gene expression.
• Structural Biology: Investigating the structural impacts of modifications on RNA molecules.
• Enzymology: Characterizing enzymes that facilitate RNA modification processes.
• Systems Biology: Integrating RNA modification data into systems-level analyses of cellular processes.

Methodology:

No computational methods or data processing steps are specified in the provided description.