MouSR

MouSR provides analysis of transcriptional data from human and mouse tissues, performing quality control, differential gene expression, gene set enrichment, and microenvironmental cell population analyses of RNA-Seq datasets.


Key Features:

  • Quality Control (QC): Performs quality control on RNA-Seq transcriptional datasets.
  • Differential Gene Expression Analysis: Identifies differentially expressed genes from RNA-Seq data.
  • Gene Set Enrichment Analysis: Performs gene set enrichment analysis to assess pathway-level changes.
  • Microenvironmental Cell Population Analyses: Analyzes microenvironmental cell populations from RNA-Seq data.
  • Customizable Analysis Parameters: Allows adjustment of analysis parameters to tailor computational analyses.

Scientific Applications:

  • Genetically Engineered Mouse Models and Organoids: Analyzes transcriptional datasets derived from genetically engineered mouse models and organoids.
  • Tumor Dataset Reproduction: Enables reproduction of key transcriptional findings demonstrated in tumor dataset analyses.
  • Signaling Pathway Analysis: Supports comprehensive analyses of signaling pathways underlying transcriptional profiles for genomics and molecular biology research.

Methodology:

Leverages advanced bioinformatic algorithms to process and analyze RNA-Seq data.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
1/12/2022
Last Updated:
1/12/2022

Operations

Publications

Ahmaderaghi B, Amirkhah R, Jackson J, Lannagan TR, Gilroy K, Malla SB, Redmond KL, Maughan T, Leedham S, Campbell AS, Sansom OJ, Lawler M, Dunne PD. The Molecular Subtyping Resource (MouSR): a user-friendly tool for rapid biological discovery from human or mouse transcriptional data. Unknown Journal. 2021. doi:10.1101/2021.08.12.456127.

Documentation