MpTheory
MpTheory models observed biological dynamics using Metabolic P (MP) theory to enable construction and inference of discrete and continuous-time MP models from time-series data.
Key Features:
- Modeling Capabilities: Implements MP theory through a collection of Java objects and algorithms to represent dynamic biological systems.
- Regression Algorithms: Provides regression methods specifically aimed at inferring MP models from time series data.
- Continuous and Discrete Time Support: Supports construction and analysis of models that operate in both continuous and discrete time intervals.
- P Systems Representation: Uses P systems as the computational model to represent metabolic processes and dynamic interactions.
- Cross-Platform Integration: Supports integration with MATLAB, GNU Octave, Mathematica, and R in addition to the core Java implementation.
Scientific Applications:
- Systems Biology Modeling: Enables modeling of metabolic and other dynamic biological processes within a discrete mathematical framework.
- Time-Series Inference: Facilitates extraction of MP models from observational time-series data to analyze system dynamics.
- Simulation of Dynamic Processes: Allows simulation and analysis of biological dynamics across continuous and discrete temporal settings and diverse experimental conditions.
Methodology:
Implements Metabolic P (MP) theory as a discrete mathematical framework, uses P systems for computational representation of metabolic processes, and applies regression algorithms to infer MP models from time-series data.
Topics
Details
- License:
- GNU Lesser General Public License (LGPL) Version 3.0
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- Java
- Added:
- 8/3/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Marchetti L, Manca V. MpTheory Java library: a multi-platform Java library for systems biology based on the Metabolic P theory. Bioinformatics. 2014;31(8):1328-1330. doi:10.1093/bioinformatics/btu814. PMID:25504849.
PMID: 25504849