MRS

MRS indexes multiple biological flat-file datasets, including EMBL, UniProt, PDB, and KEGG, to provide structured search and retrieval across nucleotide, protein, and pathway data.


Key Features:

  • Comprehensive Data Indexing: Indexes flat-file datasets from EMBL, UniProt, PDB, and KEGG to enable cross-database retrieval of nucleotide, protein, and pathway information.
  • Flexible Search Capabilities: Supports global searches across all indexed datasets and targeted searches within specific fields of individual datasets for precise information retrieval.
  • Rapid Query Processing: Employs a backend optimized for speed and reliability to process large-volume queries with fast response times.

Scientific Applications:

  • Genomic studies: Enables rapid retrieval of nucleotide sequences and annotations from EMBL for comparative and annotation analyses.
  • Proteomics: Facilitates access to UniProt protein sequences and annotations for protein identification and functional analyses.
  • Structural biology: Provides access to PDB entries for structural data retrieval and cross-referencing with sequence and functional information.
  • Systems biology and pathway analysis: Integrates KEGG pathway information with sequence and protein data to support pathway mapping and systems-level analyses.

Methodology:

Indexes flat-file datasets from biological databases to build structured indices that enable global and field-targeted searches, with a backend optimized for speed and reliability to ensure efficient query processing.

Topics

Details

Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
2/10/2017
Last Updated:
11/25/2024

Operations

Publications

Hekkelman ML, Vriend G. MRS: a fast and compact retrieval system for biological data. Nucleic Acids Research. 2005;33(Web Server):W766-W769. doi:10.1093/nar/gki422. PMID:15980580. PMCID:PMC1160183.

Documentation