msa

msa provides multiple sequence alignment within R, implementing ClustalW, ClustalOmega, and MUSCLE to generate and analyze MSAs for evolutionary and functional sequence studies.


Key Features:

  • Supported algorithms: Implements ClustalW, ClustalOmega, and MUSCLE for multiple sequence alignment.
  • Embedded implementations: Runs alignment algorithms within R without requiring external executables.
  • Bioconductor integration: Integrates with Bioconductor to operate within its data structures and workflows.
  • Visualization via shade: Provides interfaces to the shade package for customizable plotting of alignment data.

Scientific Applications:

  • Evolutionary studies: Supports sequence analysis for evolutionary studies.
  • Functional annotation: Supports sequence analysis for functional annotation.
  • Structural biology: Supports sequence analysis for structural biology.
  • Alignment visualization: Provides visualization interfaces to aid interpretation of complex alignment data.

Methodology:

Implements ClustalW, ClustalOmega, and MUSCLE algorithms within R and provides an interface to the shade package for plotting alignment data.

Topics

Collections

Details

License:
Apache-2.0
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
JavaScript
Added:
6/2/2016
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Sequence visualisation

Other operations do not define inputs or outputs.

Publications

Bodenhofer U, Bonatesta E, Horejš-Kainrath C, Hochreiter S. msa: an R package for multiple sequence alignment. Bioinformatics. 2015;31(24):3997-3999. doi:10.1093/bioinformatics/btv494. PMID:26315911.

Yachdav G, Wilzbach S, Rauscher B, Sheridan R, Sillitoe I, Procter J, Lewis SE, Rost B, Goldberg T. MSAViewer: interactive JavaScript visualization of multiple sequence alignments. Bioinformatics. 2016;32(22):3501-3503. doi:10.1093/bioinformatics/btw474. PMID:27412096. PMCID:PMC5181560.

Documentation

Downloads

Links