msa
msa provides multiple sequence alignment within R, implementing ClustalW, ClustalOmega, and MUSCLE to generate and analyze MSAs for evolutionary and functional sequence studies.
Key Features:
- Supported algorithms: Implements ClustalW, ClustalOmega, and MUSCLE for multiple sequence alignment.
- Embedded implementations: Runs alignment algorithms within R without requiring external executables.
- Bioconductor integration: Integrates with Bioconductor to operate within its data structures and workflows.
- Visualization via shade: Provides interfaces to the shade package for customizable plotting of alignment data.
Scientific Applications:
- Evolutionary studies: Supports sequence analysis for evolutionary studies.
- Functional annotation: Supports sequence analysis for functional annotation.
- Structural biology: Supports sequence analysis for structural biology.
- Alignment visualization: Provides visualization interfaces to aid interpretation of complex alignment data.
Methodology:
Implements ClustalW, ClustalOmega, and MUSCLE algorithms within R and provides an interface to the shade package for plotting alignment data.
Topics
Collections
Details
- License:
- Apache-2.0
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- JavaScript
- Added:
- 6/2/2016
- Last Updated:
- 11/25/2024
Operations
Data Inputs & Outputs
Sequence visualisation
Inputs
Publications
Bodenhofer U, Bonatesta E, Horejš-Kainrath C, Hochreiter S. msa: an R package for multiple sequence alignment. Bioinformatics. 2015;31(24):3997-3999. doi:10.1093/bioinformatics/btv494. PMID:26315911.
Yachdav G, Wilzbach S, Rauscher B, Sheridan R, Sillitoe I, Procter J, Lewis SE, Rost B, Goldberg T. MSAViewer: interactive JavaScript visualization of multiple sequence alignments. Bioinformatics. 2016;32(22):3501-3503. doi:10.1093/bioinformatics/btw474. PMID:27412096. PMCID:PMC5181560.
Documentation
Downloads
- Binarieshttps://cdn.bio.sh/
- Source codehttps://github.com/wilzbach/msa