MuGVRE

MuGVRE provides a cloud-based computational environment for 3D and 4D genomics analyses, integrating molecular dynamics simulations and next-generation sequencing (NGS) processing to support high-throughput genomic workflows.

Key Features:

• Metadata framework: Associates tools with relevant datasets to enable interoperability and management of complex genomic workflows.
• Cloud infrastructure: Leverages openNebula cloud systems for scalable compute resources supporting high-computation applications.
• Scheduling systems: Supports traditional queueing systems to handle applications with fixed computational demands.
• Elastic multi-scale execution: Employs the pyCOMPSs programming model managed by the PMES scheduler to accommodate distributed and multi-scale execution schemes.
• Workload support: Targets molecular dynamics simulations and high-throughput next-generation sequencing processing.

Scientific Applications:

• 3D and 4D genomics analyses: Enables analysis of three-dimensional and temporal genomic architectures.
• Molecular dynamics simulations: Provides infrastructure for compute-intensive molecular dynamics studies.
• Next-generation sequencing (NGS) processing: Supports high-throughput processing of NGS data for genomic analyses.
• Large-scale genomic workflows: Manages and executes complex multi-tool workflows for large-scale genomic data analysis.

Methodology:

MuGVRE uses openNebula cloud systems and an extensive metadata framework to associate tools with datasets, supports traditional queueing systems, and employs the pyCOMPSs elastic multi-scale programming model managed by the PMES scheduler for distributed or multi-scale execution.