MultiGlycan

MultiGlycan analyzes and annotates glycomic profiles derived from liquid chromatography–mass spectrometry (LC-MS) data to measure glycan compositions and abundances.

Key Features:

• Implementation: Implemented in C# for Windows systems.
• Automated annotation: Automates the annotation of glycan profiles within LC-MS datasets.
• LC‑MS data interpretation: Interprets mass spectrometry–based glycomic data to quantify glycan abundances.
• Robustness and validation: Validated across glycomic profiling datasets prepared under diverse conditions to produce consistent and reliable annotations.

Scientific Applications:

• Biomarker discovery: Identifies and quantifies glycans in complex biological samples to support exploration of glycan biomarkers associated with human diseases.
• Glycomic profiling: Enables comprehensive profiling of glycan compositions and glycosylation patterns from LC-MS data.

Methodology:

Processes LC-MS data by automating the annotation of glycan profiles and interpreting mass spectrometry–based glycomic signals to quantify glycan abundances, with validation on datasets prepared under diverse conditions.