multiMarker

multiMarker models relationships between metabolomic biomarkers and food quantity data to quantify and predict dietary intake from multiple biomarkers.


Key Features:

  • Inference of relationships: Infers relationships between two or more metabolomic biomarkers and specific food intake measurements.
  • Prediction from biomarker data: Predicts food intake quantities using available biomarker data alone.
  • Quantification of uncertainty: Produces distributions of predicted intakes rather than single-point estimates to represent prediction uncertainty.

Scientific Applications:

  • Nutrition biomarker research: Enables continuous and objective quantification of food intake using metabolomic biomarkers.
  • Epidemiological studies and clinical trials: Supports dietary exposure assessment in epidemiology and intervention studies.
  • Diet–disease and personalized nutrition research: Facilitates investigation of diet–disease relationships and biomarker-based approaches for personalized nutrition.

Methodology:

Integration of metabolomic data with statistical modeling techniques to model relationships between multiple biomarkers and food intake, predict intake from biomarkers, and generate distributions of predicted intakes.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
2/15/2022
Last Updated:
2/15/2022

Operations

Data Inputs & Outputs

Publications

D’Angelo S, Gormley IC, McNamara AE, Brennan L. multiMarker: software for modelling and prediction of continuous food intake using multiple biomarkers measurements. BMC Bioinformatics. 2021;22(1). doi:10.1186/s12859-021-04394-z. PMID:34583648. PMCID:PMC8480054.

PMID: 34583648
PMCID: PMC8480054
Funding: - European Research Council: 647783 - Science Foundation Ireland: SFI/12/RC/2289/P2