multiMarker
multiMarker models relationships between metabolomic biomarkers and food quantity data to quantify and predict dietary intake from multiple biomarkers.
Key Features:
- Inference of relationships: Infers relationships between two or more metabolomic biomarkers and specific food intake measurements.
- Prediction from biomarker data: Predicts food intake quantities using available biomarker data alone.
- Quantification of uncertainty: Produces distributions of predicted intakes rather than single-point estimates to represent prediction uncertainty.
Scientific Applications:
- Nutrition biomarker research: Enables continuous and objective quantification of food intake using metabolomic biomarkers.
- Epidemiological studies and clinical trials: Supports dietary exposure assessment in epidemiology and intervention studies.
- Diet–disease and personalized nutrition research: Facilitates investigation of diet–disease relationships and biomarker-based approaches for personalized nutrition.
Methodology:
Integration of metabolomic data with statistical modeling techniques to model relationships between multiple biomarkers and food intake, predict intake from biomarkers, and generate distributions of predicted intakes.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 2/15/2022
- Last Updated:
- 2/15/2022
Operations
Data Inputs & Outputs
Quantification
Publications
D’Angelo S, Gormley IC, McNamara AE, Brennan L. multiMarker: software for modelling and prediction of continuous food intake using multiple biomarkers measurements. BMC Bioinformatics. 2021;22(1). doi:10.1186/s12859-021-04394-z. PMID:34583648. PMCID:PMC8480054.
PMID: 34583648
PMCID: PMC8480054
Funding: - European Research Council: 647783
- Science Foundation Ireland: SFI/12/RC/2289/P2