MView (EBI)

MView (EBI) reformats BLAST, FASTA and multiple sequence alignment outputs into annotated HTML with customizable colouring to facilitate interpretation of sequence alignments and database search results.


Key Features:

  • Reformatting of search outputs: Reformats results from BLAST and FASTA sequence database searches and multiple sequence alignments into presentation-ready formats.
  • HTML markup and colouring: Produces optional HTML markup enabling customizable colouring and annotation of alignment outputs.
  • Integration with external resources: Integrates with UniProt, InterPro, ENA and Ensembl Genomes to incorporate external annotations and datasets.
  • API support: Supports RESTful and SOAP APIs for programmatic access and workflow integration.
  • Enhanced visualizations: Provides enhanced visualization formats within the Job Dispatcher framework to improve interpretation of alignments and search results.
  • Job Dispatcher integration: Operates within the EMBL-EBI Job Dispatcher framework and leverages its job management capabilities.

Scientific Applications:

  • Comparative Genomics: Enables comparative analysis of sequences across species or strains by presenting colorized alignments.
  • Protein Function Annotation: Aids protein annotation by combining alignment outputs with UniProt and InterPro information.
  • Genomic Research: Facilitates visualization of complex alignment data to identify genetic variation and evolutionary relationships.

Methodology:

Reformats BLAST and FASTA search outputs and multiple sequence alignments into optional HTML markup with customizable colouring; operates within the EMBL-EBI Job Dispatcher framework and exposes RESTful and SOAP APIs.

Topics

Collections

Details

Tool Type:
api, web application
Operating Systems:
Linux, Windows, Mac
Added:
1/29/2015
Last Updated:
5/16/2024

Operations

Publications

Madeira F, Madhusoodanan N, Lee J, Eusebi A, Niewielska A, Tivey ARN, Lopez R, Butcher S. The EMBL-EBI Job Dispatcher sequence analysis tools framework in 2024. Nucleic Acids Research. 2024;52(W1):W521-W525. doi:10.1093/nar/gkae241. PMID:38597606. PMCID:PMC11223882.

Madeira F, Pearce M, Tivey ARN, Basutkar P, Lee J, Edbali O, Madhusoodanan N, Kolesnikov A, Lopez R. Search and sequence analysis tools services from EMBL-EBI in 2022. Nucleic Acids Research. 2022;50(W1):W276-W279. doi:10.1093/nar/gkac240. PMID:35412617. PMCID:PMC9252731.

Funding: - EMBL-EBI: 824087 - BY-COVID: 101046203 - EarlyCause: 848158

Brown NP, Leroy C, Sander C. MView: a web-compatible database search or multiple alignment viewer.. Bioinformatics. 1998;14(4):380-381. doi:10.1093/bioinformatics/14.4.380.

Documentation

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