NBRP resources

NBRP resources provide centralized access to curated bioresource records and distribution metadata to support life science research.

Key Features:

• Organizational network: Comprised of 27 core resource facilities and an information center managing centralized data aggregation and distribution.
• BioResource World (BRW): An integrated database system that aggregates 30 distinct facility-specific databases.
• Database scale: Contains over 4.5 million records covering wild species, inbred lines, mutants, genetically engineered organisms, and DNA clones.
• Cross-database search: Enables searching across the 30 integrated databases from BRW.
• Search modalities: Supports summary browsing, keyword searching, and advanced queries using DNA sequences or Gene Ontology terms.
• Distribution requests: Links search results to online forms for requesting the distribution of research materials.
• Circulation system: Accepts submission of publication details resulting from research using NBRP resources.

Scientific Applications:

• Resource discovery: Locating biological materials such as wild species, inbred lines, mutants, genetically engineered organisms, and DNA clones for experimental use.
• Functional genetics: Identifying and obtaining mutants and genetically engineered organisms for gene function studies.
• Molecular biology and cloning: Retrieving DNA clones for cloning, sequencing, and molecular analyses.
• Comparative studies: Accessing inbred lines and wild species datasets for comparative and evolutionary analyses.
• Gene-centric queries: Using DNA sequence and Gene Ontology-based searches to find resources linked to specific genes or functions.
• Research tracking: Recording and aggregating publications associated with distributed NBRP resources via the circulation system.

Methodology:

BioResource World (BRW) aggregates 30 facility-specific databases and implements cross-database searches with summary browsing, keyword search, and advanced queries by DNA sequence or Gene Ontology terms; search results link to online distribution request forms and a circulation system collects publication metadata.