Database of genes from NCBI RefSeq genomes

Database of genes from NCBI RefSeq genomes provides gene-centric annotations and integrated sequence and functional data derived from NCBI Reference Sequence (RefSeq) genomes across viruses, prokaryotes, and eukaryotes to support genomic, comparative, and functional analyses.

Key Features:

• Foundation on NCBI RefSeq Genomes: Built on NCBI Reference Sequence (RefSeq) genomes encompassing viruses, prokaryotes, and eukaryotes, linking gene sequences to functional annotations.
• Integrated Content: Integrates curated and automatically processed data including genomic locations, RefSeq-derived transcript and protein sequences, and contributions from model organism databases and Gene Ontology.
• Comprehensive Data Coverage: Contains citations, gene nomenclature, genomic locations, gene products with attributes, phenotypes, sequences, interactions, variation details, maps, expression data, homologs, protein domains, and links to external databases.
• Unique Identifiers: Assigns a unique integer identifier to each Gene record for tracking and referencing.

Scientific Applications:

• Genomic Research: Supports study of genomic structures and functions across species via detailed gene annotations and sequences.
• Functional Genomics: Enables analysis of gene products, interactions, and expression patterns to investigate gene function and regulation.
• Comparative Genomics: Facilitates cross-species comparisons using homologous gene data.
• Phenotypic Studies: Supports investigation of gene-associated phenotypes, including genetic diseases and traits.

Methodology:

Data are incorporated through automated processing and expert curation, integrating RefSeq and contributor database information.