ncRDense

ncRDense classifies non-coding RNA (ncRNA) sequences into families using a deep learning architecture to support analysis of ncRNA roles in transcription, translation, and disease.


Key Features:

  • Deep Learning Architecture: ncRDense employs a deep learning-based architecture specifically tailored for classification of ncRNA families.
  • Comparative Performance: In comparative studies, ncRDense has demonstrated performance on par with existing state-of-the-art methods for ncRNA classification.

Scientific Applications:

  • Understanding Biological Processes: Accurate classification of ncRNA families supports analysis of their roles in transcription and translation.
  • Disease Mechanism Elucidation: The tool aids identification of specific ncRNAs associated with diseases to inform studies of disease mechanisms.
  • Treatment Design: Insights from ncRNA classification can inform development of targeted therapies and personalized medicine approaches.

Methodology:

ncRDense utilizes a deep learning framework with an architecture optimized for high-accuracy discrimination among ncRNA families.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
12/1/2021
Last Updated:
12/1/2021

Operations

Publications

Chantsalnyam T, Siraj A, Tayara H, Chong KT. ncRDense: A novel computational approach for classification of non-coding RNA family by deep learning. Genomics. 2021;113(5):3030-3038. doi:10.1016/j.ygeno.2021.07.004. PMID:34242708.

PMID: 34242708
Funding: - Ministry of Science and ICT, South Korea: 2020R1A2C2005612, NRF-2017M3C7A1044816 - Ministry of Trade, Industry and Energy: 20204010600470

Links