ncRI

ncRI catalogs validated non-coding RNAs implicated in inflammatory responses across human, mouse, and rat to support mechanistic and comparative studies.

Key Features:

• Extensive Data Collection: The database contains 11,166 entries documenting ncRNAs including 1,976 microRNAs (miRNAs), 1,377 long non-coding RNAs (lncRNAs), and 107 other ncRNAs from human, mouse, and rat.
• Detailed Annotations: Each entry provides the ncRNA name, associated inflammatory diseases, mechanistic insights, experimental validation techniques (microarray, RNA-seq, qRT-PCR), experimental sample types (cell lines and/or tissues), and expression patterns indicating up-regulation or down-regulation in inflammatory conditions.
• Reference Integration: Entries include PubMed IDs, publication years, and paper titles linking to original research.

Scientific Applications:

• Research on Immunotherapy: Enables study of ncRNA-mediated regulation of immune responses relevant to immunotherapy research.
• Mechanistic Studies: Supports identification of ncRNAs as mechanistic contributors, biomarkers, or therapeutic targets in inflammatory diseases.
• Cross-Species Analysis: Facilitates comparative and translational studies using human, mouse, and rat data.

Methodology:

No computational methods were specified in the provided description.