Newt-VE

Newt-VE visualizes, constructs, and analyzes biological pathways to support systems biology research and interpretation of complex molecular networks.

Key Features:

• Standard Format Compatibility: Supports Systems Biological Graphical Notation (SBGN), Systems Biology Markup Language (SBML), and Simple Interaction Format (SIF) to enable interoperability with existing biological data sets.
• Network Visualization Engine: Built on Cytoscape.js to visualize complex networks and provide customizable visualization and analytical representations.
• Pathway Construction and Editing: Provides functionality for building and editing biological maps and integrating them with other datasets for downstream analysis.

Scientific Applications:

• Systems Biology Pathway Modeling: Visualization and analysis of cellular processes and molecular interaction networks.
• Data Interpretation and Hypothesis Generation: Interpretation of complex experimental datasets to support generation of mechanistic hypotheses.
• Experimental Result Validation: Comparison and validation of experimental results against curated pathway maps.

Methodology:

Integration of visualization techniques with Cytoscape.js and additional libraries to enable pathway construction, editing, and analysis, with support for SBGN, SBML, and SIF formats.