nf-core-eager
nf-core-eager provides reproducible, Nextflow-based workflows for analysis of ancient DNA (aDNA) genomic data.
Key Features:
- Reproducibility: Implements reproducible analyses and standardized pipelines for ancient genomic data.
- Integration of contemporary practices: Incorporates routine and up-to-date methods in ancient genomic analysis.
- nf-core development standards: Developed under the nf-core initiative with established software development standards and maintenance.
- Workflow orchestration: Employs Nextflow to orchestrate complex bioinformatics analyses.
Scientific Applications:
- Archaeological, palaeontological, and biological research: Supports genomic investigations using ancient DNA across archaeological, palaeontological, and biological contexts.
- Historical population dynamics: Enables analysis of past population structure and dynamics from ancient genomic data.
- Evolutionary biology: Facilitates studies of evolutionary relationships and processes using ancient genomes.
- Conservation genetics: Can be applied to conservation genetics investigations using aDNA-derived genomic information.
Methodology:
Workflows are orchestrated using the Nextflow workflow management system.
Topics
Details
- License:
- MIT
- Maturity:
- Mature
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Mac
- Programming Languages:
- Groovy
- Added:
- 10/25/2021
- Last Updated:
- 10/25/2021
Operations
Data Inputs & Outputs
Aggregation
Outputs
Publications
Fellows Yates JA, Lamnidis TC, Borry M, Andrades Valtueña A, Fagernäs Z, Clayton S, Garcia MU, Neukamm J, Peltzer A. Reproducible, portable, and efficient ancient genome reconstruction with nf-core/eager. PeerJ. 2021;9:e10947. doi:10.7717/peerj.10947. PMID:33777521. PMCID:PMC7977378.
DOI: 10.7717/peerj.10947
PMID: 33777521
PMCID: PMC7977378
Funding: - ERC Starting Grant project FoodTransforms: ERC-2015-StG 678901-Food-Transforms
- European Union’s Horizon 2020 Research and Innovation Programme: 851511
Documentation
Command-line options
https://nf-co.re/eagerInstallation instructions
https://nf-co.re/eagerDownloads
- Source codehttps://github.com/nf-core/eager
Links
Repository', 'Issue tracker
https://github.com/nf-core/eager