nf-core-eager

nf-core-eager provides reproducible, Nextflow-based workflows for analysis of ancient DNA (aDNA) genomic data.


Key Features:

  • Reproducibility: Implements reproducible analyses and standardized pipelines for ancient genomic data.
  • Integration of contemporary practices: Incorporates routine and up-to-date methods in ancient genomic analysis.
  • nf-core development standards: Developed under the nf-core initiative with established software development standards and maintenance.
  • Workflow orchestration: Employs Nextflow to orchestrate complex bioinformatics analyses.

Scientific Applications:

  • Archaeological, palaeontological, and biological research: Supports genomic investigations using ancient DNA across archaeological, palaeontological, and biological contexts.
  • Historical population dynamics: Enables analysis of past population structure and dynamics from ancient genomic data.
  • Evolutionary biology: Facilitates studies of evolutionary relationships and processes using ancient genomes.
  • Conservation genetics: Can be applied to conservation genetics investigations using aDNA-derived genomic information.

Methodology:

Workflows are orchestrated using the Nextflow workflow management system.

Topics

Details

License:
MIT
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Mac
Programming Languages:
Groovy
Added:
10/25/2021
Last Updated:
10/25/2021

Operations

Data Inputs & Outputs

Publications

Fellows Yates JA, Lamnidis TC, Borry M, Andrades Valtueña A, Fagernäs Z, Clayton S, Garcia MU, Neukamm J, Peltzer A. Reproducible, portable, and efficient ancient genome reconstruction with nf-core/eager. PeerJ. 2021;9:e10947. doi:10.7717/peerj.10947. PMID:33777521. PMCID:PMC7977378.

PMID: 33777521
PMCID: PMC7977378
Funding: - ERC Starting Grant project FoodTransforms: ERC-2015-StG 678901-Food-Transforms - European Union’s Horizon 2020 Research and Innovation Programme: 851511

Documentation

Command-line options
https://nf-co.re/eager
Installation instructions
https://nf-co.re/eager

Downloads

Links

Repository', 'Issue tracker
https://github.com/nf-core/eager