nf-core

nf-core provides standardized analysis pipelines built on Nextflow, facilitating FAIR bioinformatics research through a library of modules and subworkflows that streamline data analysis workflows.

Key Features:

• Standardized Pipelines: nf-core provides standardized analysis pipelines that follow community-agreed best practices for bioinformatics data analysis.
• Modular Components: The recent development of Nextflow Domain-Specific Language 2 (DSL2) allows pipeline components to be shared and combined across projects.
• Library of Modules and Subworkflows: nf-core maintains a library of modules and subworkflows that can be integrated into any Nextflow pipeline, enabling research communities to progressively transition to nf-core best practices.
• Community-Driven Development: nf-core enables collaboration within a community of over 8,000 members, allowing faster development and improved interoperability.

Scientific Applications:

• Farmed Animal Genomics: Six European research consortia grouped under the EuroFAANG umbrella have adopted nf-core standards to harmonize their data analysis procedures for farmed animal genomics research.
• Large Consortium Harmonization: nf-core adoption enables large research consortia to standardize and harmonize their data analysis procedures across multiple projects and institutions.

Methodology:

nf-core pipelines are built on Nextflow, a command-line workflow management system, utilizing Nextflow Domain-Specific Language 2 (DSL2) for modular pipeline component sharing and integration.