NGSView

NGSView provides visualization and editing of next-generation sequence alignments to enable analysis and manipulation of large-scale sequencing datasets.

Key Features:

• Visualization and manipulation: Supports visualization and editing of next-generation sequence alignments and individual reads.
• Scalability: Capable of handling millions of sequences simultaneously for large-scale datasets.
• Extensibility: Designed to be extensible to accommodate additional analysis functions and workflows.

Scientific Applications:

• Genomic research: Facilitates inspection and analysis of genome-scale sequencing alignments.
• Variant calling: Enables manual review and adjustment of alignments relevant to variant detection.
• Comparative genomics: Supports comparison of aligned sequences across samples or references.
• Transcriptome analysis: Assists examination of aligned RNA-seq reads for transcript-level investigations.

Methodology:

Performs simultaneous visualization and manipulation of extensive next-generation sequencing alignments to manage and inspect large sequencing datasets.