NOVOWrap
NOVOWrap automates assembly and standardization of plastid genomes from next-generation sequencing data for genomics and evolutionary studies.
Key Features:
- Automated plastid genome assembly: Performs automated assembly of plastid genomes from next-generation sequencing datasets.
- Assembly validation: Validates assembly results to ensure correctness of plastid genome reconstructions.
- Genome structure standardization: Standardizes plastid genome structures to provide consistent representations.
- Resource-efficient computation: Operates using affordable computer resources.
- Benchmarking: Benchmarked against plastid genomes of 11 species spanning lycopods, gymnosperms, and angiosperms.
- Standardized data generation: Generates reliable, standardized genomic data to facilitate data exchange and downstream analyses.
Scientific Applications:
- Plastid genomics: Assembly and standardization of plastid genomes for genomics and evolutionary biology research.
- Comparative plant genomics: Enables comparative analyses across lycopods, gymnosperms, and angiosperms using standardized plastid genomes.
- Downstream analyses and data sharing: Provides standardized outputs to support downstream analytical applications and data exchange from next-generation sequencing studies.
Methodology:
Automated assembly from next-generation sequencing data, validation of assembly results, standardization of plastid genome structures, and benchmarking against plastid genomes of 11 species across lycopods, gymnosperms, and angiosperms.
Topics
Details
- License:
- AGPL-3.0
- Tool Type:
- command-line tool, desktop application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- Python
- Added:
- 10/25/2021
- Last Updated:
- 10/25/2021
Operations
Publications
Wu P, Xu C, Chen H, Yang J, Zhang X, Zhou S. <scp>NOVOWrap</scp>: An automated solution for plastid genome assembly and structure standardization. Molecular Ecology Resources. 2021;21(6):2177-2186. doi:10.1111/1755-0998.13410. PMID:33934526.
PMID: 33934526
Funding: - National Natural Science Foundation of China: 31872679
Links
Issue tracker
https://github.com/wpwupingwp/novowrap/issues