NOVOWrap

NOVOWrap automates assembly and standardization of plastid genomes from next-generation sequencing data for genomics and evolutionary studies.


Key Features:

  • Automated plastid genome assembly: Performs automated assembly of plastid genomes from next-generation sequencing datasets.
  • Assembly validation: Validates assembly results to ensure correctness of plastid genome reconstructions.
  • Genome structure standardization: Standardizes plastid genome structures to provide consistent representations.
  • Resource-efficient computation: Operates using affordable computer resources.
  • Benchmarking: Benchmarked against plastid genomes of 11 species spanning lycopods, gymnosperms, and angiosperms.
  • Standardized data generation: Generates reliable, standardized genomic data to facilitate data exchange and downstream analyses.

Scientific Applications:

  • Plastid genomics: Assembly and standardization of plastid genomes for genomics and evolutionary biology research.
  • Comparative plant genomics: Enables comparative analyses across lycopods, gymnosperms, and angiosperms using standardized plastid genomes.
  • Downstream analyses and data sharing: Provides standardized outputs to support downstream analytical applications and data exchange from next-generation sequencing studies.

Methodology:

Automated assembly from next-generation sequencing data, validation of assembly results, standardization of plastid genome structures, and benchmarking against plastid genomes of 11 species across lycopods, gymnosperms, and angiosperms.

Topics

Details

License:
AGPL-3.0
Tool Type:
command-line tool, desktop application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
Python
Added:
10/25/2021
Last Updated:
10/25/2021

Operations

Publications

Wu P, Xu C, Chen H, Yang J, Zhang X, Zhou S. <scp>NOVOWrap</scp>: An automated solution for plastid genome assembly and structure standardization. Molecular Ecology Resources. 2021;21(6):2177-2186. doi:10.1111/1755-0998.13410. PMID:33934526.

PMID: 33934526
Funding: - National Natural Science Foundation of China: 31872679

Links